One of every four people in Turkey suffers from reduced MTHFR enzyme activity. In people with reduced MTHFR enzyme activity, the folic acid consumed in standard form cannot activate and cannot have enough effect.

The 1sr generation of folate is the folic acid obtained from foods, the 2nd generation of folate is the form obtained from standard folic acid supplements, and the 3rd generation of folate is the low-soluble form of active folate. The 4th Generation of active folate is the active form of folic acid and can have impact in the body without needing any transformation.